I previously had an HP 5 button optical comfort mouse but these are now end of life for some reason with no apparent like-for-like replacement.

One 'slit' button each side meant no uncomfortable straining for the right button and kept things nice and simple. Today's range of mice seems to be vying with mobile phone handsets in the straining discomfort stakes.

  • Which hand are you using your mouse with? Feb 24 '20 at 8:10
  • Also, do you allow for software setup? E.g. you would be required to program which button is which in mouse vendor software before using it for the first time? Feb 24 '20 at 16:10
  • If you're OK with software programmable buttons, which OS does the mouse need to be compatible with?
    – Romen
    Feb 24 '20 at 21:58
  • @Romen usually those soft programmable mice have settings saved in the mouse itself. At least for the DPI, haven't tested it with buttons. Feb 26 '20 at 7:54
  • @JanDorniak, We still need to know which OS they will need, what good is the on-board memory if the software for programming it doesn't work for you?
    – Romen
    Feb 26 '20 at 13:13

I use the ergonomic Adesso iMouse E1 — five buttons and scroll wheel.


Mine is right-handed, but the iMouse E7-TAA is for left hands.


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